Lignospan Standard – Local Anesthetic Injection (50 x 1.7ml)

Lignospan Standard is a sterile injectable local anesthetic solution widely used in dental and minor surgical procedures. It combines Lidocaine Hydrochloride with Epinephrine, providing rapid onset anesthesia with effective pain control and improved procedural precision.

This product is trusted by dental professionals and clinics for its fast action, reliable performance, and consistent results.

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Composition

Each single-dose cartridge (1.7 ml) contains:

• Lidocaine Hydrochloride (local anesthetic)
• Epinephrine (as Bitartrate) (vasoconstrictor to prolong effect)
• Excipients q.s.

Dosage form: Sterile injectable solution

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Mechanism of Action

Lidocaine works by stabilizing neuronal membranes, inhibiting ionic fluxes required for the initiation and conduction of nerve impulses. This results in effective local anesthesia.

Epinephrine helps reduce blood flow at the injection site, prolonging the anesthetic effect and minimizing systemic absorption.

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Onset & Duration

• Infiltration anesthesia (dental use): onset typically under 2 minutes
• Nerve block anesthesia: onset approximately 2–4 minutes

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Indications

Lignospan Standard is indicated for:

• Local anesthesia in dental procedures
• Nerve block techniques
• Infiltration anesthesia for minor surgical procedures

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Dosage & Administration

• Dosage should be individualized based on:
  • Patient condition
  • Type of procedure
  • Vascularity of the treatment area
• Typical initial dose:
  1.0 – 5.0 ml (approximately ½ to 2.5 cartridges)
• Always use the lowest effective dose to achieve adequate anesthesia
• Route of administration: Injection

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Contraindications

• Hypersensitivity to amide-type local anesthetics
• Allergy to any component of the formulation

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Possible Side Effects

• Neurological reactions: may occur depending on technique, dosage, and patient condition
• Allergic reactions (rare):
  • Skin rash, urticaria
  • Edema
  • Bronchospasm or difficulty breathing
  • Anaphylaxis (extremely rare)

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Drug Interactions

Use with caution in patients taking:

• Monoamine Oxidase Inhibitors (MAOIs)
• Tricyclic antidepressants
• Phenothiazines

These combinations may cause blood pressure fluctuations.

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Warnings & Precautions

• May cause methemoglobinemia in rare cases
• Use cautiously in patients with:
  • Severe cardiovascular conditions
  • Liver impairment (metabolism occurs in the liver)
  • Shock or heart block
• Adjust dosage for children based on age and body weight

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Use in Pregnancy & Breastfeeding

• Use with caution; limited data available
• Consult a healthcare professional before use

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Overdose

Although rare, overdose may lead to severe symptoms similar to side effects. Immediate medical attention is required if symptoms occur.

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Storage

• Store in a cool, dry place below 30°C
• Protect from light
• Keep out of reach of children

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Disadvantages

• May cause pain at injection site
• Risk of allergic reactions in sensitive individuals

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Packaging

• 50 cartridges x 1.7 ml per box

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Why Choose Lignospan Standard

Lignospan Standard offers a fast, reliable, and clinically proven anesthetic solution, making it a preferred choice for dental professionals seeking consistent performance and patient comfort.